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1

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Equipment Qualification, Process and Cleaning Validation

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 382 KB

english, 2015

2

Real-time monitoring of drug concentration in a continuous powder mixing process using NIR spectroscopy

Aditya U. Vanarase, Manel Alcalà, Jackeline I. Jerez Rozo, Fernando J. Muzzio, Rodolfo J. Romañach

Journal:

Chemical Engineering Science

Year:

2010

Language:

english

File:

PDF, 471 KB

english, 2010

3

Blend uniformity analysis using stream sampling and near infrared spectroscopy

Manuel Popo, Saly Romero-Torres, Carlos Conde, Rodolfo J. Romañach

Journal:

AAPS PharmSciTech

Year:

2002

Language:

english

File:

PDF, 421 KB

english, 2002

4

Prediction of dissolution profiles by non-destructive near infrared spectroscopy in tablets subjected to different levels of strain

Hernandez, Eduardo, Pawar, Pallavi, Keyvan, Golshid, Wang, Yifan, Velez, Natasha, Callegari, Gerardo, Cuitino, Alberto, Michniak-Kohn, Bozena, Muzzio, Fernando J., Romañach, Rodolfo J.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

5

In-Line Near-Infrared (NIR) and Raman Spectroscopy Coupled with Principal Component Analysis (PCA) for In Situ Evaluation of the Transesterification Reaction

Fontalvo-Gómez, Miriam, Colucci, José A., Velez, Natasha, Romañach, Rodolfo J.

Journal:

Applied Spectroscopy

Year:

2013

Language:

english

File:

PDF, 448 KB

english, 2013

6

Near infrared spectroscopic calibration models for real time monitoring of powder density

Román-Ospino, Andrés D., Singh, Ravendra, Ierapetritou, Marianthi, Ramachandran, Rohit, Méndez, Rafael, Ortega-Zuñiga, Carlos, Muzzio, Fernando J., Romañach, Rodolfo J.

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 6.45 MB

english, 2016

7

Process analytical technology in continuous manufacturing of a commercial pharmaceutical product

Vargas, Jenny M., Nielsen, Sarah, Cárdenas, Vanessa, Gonzalez, Anthony, Aymat, Efrain Y., Almodovar, Elvin, Classe, Gustavo, Colón, Yleana, Sanchez, Eric, Romañach, Rodolfo J.

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

8

Determining the number of significant figures for reporting NIR results

Cárdenas, Vanessa, Romañach, Rodolfo J

Journal:

Year:

2018

Language:

english

File:

PDF, 82 KB

english, 2018

9

Feed frame: the last processing step before the tablet compaction in pharmaceutical manufacturing

Sierra-Vega, Nobel O., Romañach, Rodolfo J., Méndez, Rafael

Journal:

International Journal of Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 748 KB

english, 2019

10

Preparation and characterization of hydroxypropyl methyl cellulose films containing stable BCS Class II drug nanoparticles for pharmaceutical applications

Lucas Sievens-Figueroa, Anagha Bhakay, Jackeline I. Jerez-Rozo, Natasha Pandya, Rodolfo J. Romañach, Bozena Michniak-Kohn, Zafar Iqbal, Ecevit Bilgili, Rajesh N. Davé

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.72 MB

english, 2012

11

Evaluation of Three Approaches for Real-Time Monitoring of Roller Compaction with Near-Infrared Spectroscopy

David Acevedo, Ariel Muliadi, Arun Giridhar, James D. Litster, Rodolfo J. Romañach

Journal:

AAPS PharmSciTech

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

12

Fast drying of biocompatible polymer films loaded with poorly water-soluble drug nano-particles via low temperature forced convection

Susarla, Ramana, Sievens-Figueroa, Lucas, Bhakay, Anagha, Shen, Yueyang, Jerez-Rozo, Jackeline I., Engen, William, Khusid, Boris, Bilgili, Ecevit, Romañach, Rodolfo J., Morris, Kenneth R., Michniak-Ko

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 1.63 MB

english, 2013

13

Real time monitoring of blend density for coupled feed-forward/feed-back control of a continuous direct compaction tablet manufacturing process

Román-Ospino, Ravendra Andrés D., Romañach, Rodolfo J., Ierapetritou, Marianthi, Ramachandran, Rohit

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 4.36 MB

english, 2015

14

Adequacy and verifiability of pharmaceutical mixtures and dose units by variographic analysis (Theory of Sampling) – A call for a regulatory paradigm shift

Esbensen, Kim H., Román-Ospino, Andrés D., Sanchez, Adriluz, Romañach, Rodolfo J.

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 2.18 MB

english, 2016

15

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Mixing of Pharmaceutical Solid-Liquid Suspensions

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 1014 KB

english, 2015

16

Evaluation of Analytical and Sampling Errors in the Prediction of the Active Pharmaceutical Ingredient Concentration in Blends From a Continuous Manufacturing Process

Vargas, Jenny M., Roman-Ospino, Andres D., Sanchez, Eric, Romañach, Rodolfo J.

Journal:

Journal of Pharmaceutical Innovation

Year:

2017

Language:

english

File:

PDF, 1.13 MB

english, 2017

17

Development of Near Infrared Spectroscopic Calibration Models for In-line Determination of Low Drug Concentration, Bulk Density, and Relative Specific Void Volume within a Feed Frame

Ortega-Zúñiga, Carlos, la Rosa, Carlos Pinzón-De, Román-Ospino, Andrés D., Serrano-Vargas, Alberto, Romañach, Rodolfo J., Méndez, Rafael

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2018

Language:

english

File:

PDF, 846 KB

english, 2018

18

A sampling system for flowing powders based on the theory of sampling

Alvarado-Hernández, Barbara B., Sierra-Vega, Nobel O., Martínez-Cartagena, Pedro, Hormaza, Manuel, Méndez, Rafael, Romañach, Rodolfo J.

Journal:

International Journal of Pharmaceutics

Year:

2020

File:

PDF, 1.08 MB

2020

19

Analysis of low content drug tablets by transmission near infrared spectroscopy: Selection of calibration ranges according to multivariate detection and quantitation limits of PLS models

Manel Alcalà, Joshua León, Jorge Ropero, Marcelo Blanco, Rodolfo J. Romañach

Journal:

Journal of Pharmaceutical Sciences

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

20

Deconvolution of chemical and physical information from intact tablets NIR spectra: Two- and three-way multivariate calibration strategies for drug quantitation

Manel Alcalà, Jorge Ropero, Raquel Vázquez, Rodolfo J. Romañach

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 253 KB

english, 2009

21

Complementary near-infrared and raman chemical imaging of pharmaceutical thin films

Jackeline I. Jérez Rozo, Anna Zarow, Bo Zhou, Rodolfo Pinal, Zafar Iqbal, Rodolfo J. Romañach

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 503 KB

english, 2011

22

Atomic force measurements of 16-mercaptohexadecanoic acid and its salt with CH3, OH, and CONHCH3 functionalized self-assembled monolayers

Angel L. Morales-Cruz, Rolando Tremont, Ramón Martínez, Rodolfo Romañach, Carlos R. Cabrera

Journal:

Applied Surface Science

Year:

2005

Language:

english

File:

PDF, 311 KB

english, 2005

23

Design and In-line Raman Spectroscopic Monitoring of a Protein Batch Crystallization Process

Joanna Mercado, Manel Alcalà, Krizia M. Karry, Jorge L. Ríos-Steiner, Rodolfo J. Romañach

Journal:

Journal of Pharmaceutical Innovation

Year:

2008

Language:

english

File:

PDF, 382 KB

english, 2008

24

Near-infrared Spectroscopy for the In-line Characterization of Powder Voiding Part I: Development of the Methodology

Jorge Ropero, Lauren Beach, Manel Alcalà, Raizza Rentas, Rajesh N. Davé, Rodolfo J. Romañach

Journal:

Journal of Pharmaceutical Innovation

Year:

2009

Language:

english

File:

PDF, 342 KB

english, 2009

25

Near-Infrared Spectroscopy for the In-Line Characterization of Powder Voiding Part II: Quantification of Enhanced Flow Properties of Surface Modified Active Pharmaceutical Ingredients

Lauren Beach, Jorge Ropero, Ajit Mujumdar, Manel Alcalà, Rodolfo J. Romañach, Rajesh N. Davé

Journal:

Journal of Pharmaceutical Innovation

Year:

2010

Language:

english

File:

PDF, 718 KB

english, 2010

26

A novel method for analyzing thick tablets by near infrared spectroscopy

José L. Ramirez, Michael K. Bellamy, Rodolfo J. Romañach

Journal:

AAPS PharmSciTech

Year:

2001

Language:

english

File:

PDF, 792 KB

english, 2001

27

Quantitation of drug content in a low dosage formulation by transmission near infrared spectroscopy

Carlos Peroza Meza, María A. Santos, Rodolfo J. Romañach

Journal:

AAPS PharmSciTech

Year:

2006

Language:

english

File:

PDF, 249 KB

english, 2006

28

Near-Infrared Spectroscopic Method for Real-Time Monitoring of Pharmaceutical Powders During Voiding

Barajas, Martha J., Cassiani, Alex Rodriguez, Vargas, Wandylis, Conde, Carlos, Ropero, Jorge, Figueroa, Jorge, Romañach, Rodolfo J.

Journal:

Applied Spectroscopy

Year:

2007

Language:

english

File:

PDF, 362 KB

english, 2007

29

Near-Infrared Chemical Imaging Slope as a New Method to Study Tablet Compaction and Tablet Relaxation

Ropero, Jorge, Colon, Yleana, Johnson-Restrepo, Boris, Romanach, Rodolfo J.

Journal:

Applied Spectroscopy

Year:

2011

Language:

english

File:

PDF, 2.45 MB

english, 2011

30

Effects of stabilizers on particle redispersion and dissolution from polymer strip films containing liquid antisolvent precipitated griseofulvin particles

Beck, Christian, Sievens-Figueroa, Lucas, Gärtner, Konstantin, Jerez-Rozo, Jackeline I., Romañach, Rodolfo J., Bilgili, Ecevit, Davé, Rajesh N.

Journal:

Powder Technology

Year:

2013

Language:

english

File:

PDF, 2.38 MB

english, 2013

31

MIA and NIR Chemical Imaging for pharmaceutical product characterization

José M. Prats-Montalbán, Jackeline I. Jerez-Rozo, Rodolfo J. Romañach, Alberto Ferrer

Journal:

Chemometrics and Intelligent Laboratory Systems

Year:

2012

Language:

english

File:

PDF, 3.42 MB

english, 2012

32

Collagen abundance in mechanically stimulated osteoblast cultures using near infrared microscopy

Boada-Lopez, Jairo, DeJesus-Maldonado, Idaris, Jerez, Jackeline, Romañach, Rodolfo, Diffoot-Carlo, Nanette, Sundaram, Paul

Journal:

Journal of Biomechanics

Year:

2013

Language:

english

File:

PDF, 3.07 MB

english, 2013

33

Analysis of powder phenomena inside a Fette 3090 feed frame using in-line NIR spectroscopy

Mateo-Ortiz, Daniel, Colon, Yleana, Romañach, Rodolfo J., Méndez, Rafael

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2014

Language:

english

File:

PDF, 3.36 MB

english, 2014

34

Raman spectroscopy for in-line and off-line quantification of poorly soluble drugs in strip films

Zhang, Jun, Ying, Ye, Pielecha-Safira, Barbara, Bilgili, Ecevit, Ramachandran, Rohit, Romañach, Rodolfo, Davé, Rajesh N., Iqbal, Zafar

Journal:

International Journal of Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

35

Near Infrared Method Development for a Continuous Manufacturing Blending Process

Colón, Yleana M., Florian, Miguel A., Acevedo, David, Méndez, Rafael, Romañach, Rodolfo J.

Journal:

Journal of Pharmaceutical Innovation

Year:

2014

Language:

english

File:

PDF, 736 KB

english, 2014

36

Preliminary Studies for Interfacing Countercurrent Chromatography (CCC) with Fourier Transform Infrared (FT-IR) Spectrometry

Romanach, Rodolfo J., de Haseth, James A., Ito, Yoichiro

Journal:

Journal of Liquid Chromatography

Year:

1985

Language:

english

File:

PDF, 343 KB

english, 1985

37

Comparison of Columns for the Analytical High Speed Countercurrent Chromatograph

Romañach, Rodolfo J., de Haseth, James A.

Journal:

Journal of Liquid Chromatography

Year:

1988

Language:

english

File:

PDF, 474 KB

english, 1988

38

Flow Cell CCC/FT-IR Spectrometry

Romañach, Rodolfo J., de Haseth, James A.

Journal:

Journal of Liquid Chromatography

Year:

1988

Language:

english

File:

PDF, 598 KB

english, 1988

39

Near infrared spectroscopic transmittance measurements for pharmaceutical powder mixtures

Sánchez, Adriluz, Román-Ospino, Andrés D., Martínez, Mirna, Mercado, Joseph, Alonso, Camila, Romañach, Rodolfo J.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

40

Characterization of resonant acoustic mixing using near-infrared chemical imaging

Osorio, Juan G., Hernández, Eduardo, Romañach, Rodolfo J., Muzzio, Fernando J.

Journal:

Powder Technology

Year:

2016

Language:

english

File:

PDF, 2.73 MB

english, 2016

41

SPIE Proceedings [SPIE 1985 International Conference on Fourier and Computerized Infrared Spectroscopy - Ottawa, Canada (Tuesday 1 January 1985)] Fourier and Computerized Infrared Spectroscopy - High Speed Countercurrent Chromatography/Fourier Transform Infrared (HSCCC/FT-IR) Spectrometry

Romanach, Rodolfo J., de Haseth, James A., Cameron, David G., Grasselli, Jeannette G.

Year:

1985

Language:

english

File:

PDF, 68 KB

english, 1985

42

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Mixing Theory

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

43

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Powder Blending Equipment

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

44

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Particles and Blending

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 550 KB

english, 2015

45

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Sampling and Determination of Adequacy of Mixing

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 272 KB

english, 2015

46

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Continuous Powder Mixing

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

47

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Turbulent Mixing Fundamentals

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 734 KB

english, 2015

48

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Fluid Mixing Equipment Design

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

49

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Dispersion of Fine Powders in Liquids

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 1.47 MB

english, 2015

50

Pharmaceutical Blending and Mixing (Cullen/Pharmaceutical Blending and Mixing) || Wet Granulation and Mixing

Cullen, P.J., Romañach, Rodolfo J., Abatzoglou, Nicolas, Rielly, Chris D.

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

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